Diabetic Kidney Disease

Home Diabetic Kidney Disease

Diabetic Kidney Disease

Diabetic Kidney Disease (DKD), also known as diabetic nephropathy, is a serious complication of both type 1 and type 2 diabetes and the leading cause of kidney failure, or End-stage Renal Disease (ESRD), globally. This condition arises when persistently elevated blood sugar levels progressively damage the delicate filtering units within the kidneys. Over time, this damage compromises the kidneys' ability to effectively filter waste products and excess fluid from the bloodstream.

Symptoms:

  • High blood pressure
  • Fatigue or weakness
  • Increased urination, especially at night
  • Foamy or bubbly urine from protein leaking into urine
  • Swelling in hands, feet, ankles, or around the eyes due to fluid retention etc.

What Happens in Diabetic Kidney Disease?

  • Kidney scarring- Ongoing injury leads to scarring (fibrosis), which permanently reduces kidney function.
  • Blood vessel damage- High glucose levels injure the glomeruli, making them thickened and less efficient.
  • Leakage of protein– Damaged filters allow important proteins, especially albumin, to leak into the urine (proteinuria).
  • Reduced filtering- As damage progresses, the kidneys lose their ability to clean the blood properly, causing waste buildup.
  • Kidney failure- If untreated, this damage worsens, leading to chronic kidney disease and eventually kidney failure / end-stage renal disease).